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New Paper +++ One bout of endurance exercise does not change gene expression or proliferation in a C26 colon carcinoma in immunocompetent mice

Sport- und Gesundheitswissenschaften, TUSPFSP-newscat-exercisebiology |


Volcano plot visualising the effect of one bout of running on gene expression in a C26 mouse colon tumour in female (A; three samples rest, three samples post-run) and male (B; two samples rest, three samples post-run) mice.

Exercise typically reduces tumour growth, proliferation and improves outcomes. Many of these effects require exercise to change gene expression within a tumour, but whether exercise  actually affects gene expression within a tumour has not been investigated yet. The aim of our recent study was, therefore, to find out whether one bout of endurance exercise alters gene expression and proliferation in a C26 carcinoma in immunocompetent mice.

We currently published our results in Journal of Cancer Research and Clinical Oncology:
Mahnic N, Geremia A, Straub T, Zorzato S, Schönfelder M, von Lüttichau I, Steiger K, Saller MM, Blaauw B, Wackerhage H.
One bout of endurance exercise does not change gene expression or proliferation in a C26 colon carcinoma in immunocompetent mice.
J Cancer Res Clin Oncol. 2023 Oct 16. doi: 10.1007/s00432-023-05447-x. PMID: 37840045